Breathe Round Table

A Cystic Fibrosis Patient’s Journey To A Successful Lung Transplant

If you were to speak with Jeff, 32, a financial professional from Westlake Village, CA, you’d be hard pressed to guess that he was ever sick. In fact, although he is now a happily married father of one, Jeff has been living with cystic fibrosis (CF) for his entire life and things were very different just two years ago.

When Jeff was growing up, like many young people living with CF, he was relatively unaffected by his condition. “When I was 10, my parents explained CF, but they were always incredibly supportive and made it clear that they would help me live as normal a life as possible,” Jeff explained. “My parents introduced me to sports and physical activities because they’re a big part of normal childhoods. I played hockey, soccer and practiced jujitsu.” Although Jeff knew lung transplantation was a reality for some CF patients, he was also aware of developmental treatments and was optimistic that there would be a cure before that time came.

Jeff’s lung capacity slowly declined over time and he ultimately had to quit competitive sports during college because his respiratory endurance was significantly impaired. While he was still able to casually participate in athletics, his condition deteriorated in 2012, severely limiting his physical endurance and exercise capacity. When his lung collapsed abruptly in April of 2013, he was faced with the gravity of his situation and learned he needed a lung transplant. His doctors put him on the waiting list.

“I was at the point where I needed oxygen around the clock. Eventually, I couldn’t even walk a few feet, or use the elliptical machine for a few seconds, without having to stop to catch my breath.”

In order to become healthy enough to undergo lung transplant surgery, Jeff needed to exercise, but cumbersome oxygen equipment and an already diminished respiratory capacity had made mobility nearly impossible. To address these problems, Jeff’s doctors and care team decided the best thing for him was to begin treatment with Breathe Technologies’ one-pound wearable ventilator (Non-Invasive Open Ventilation (NIOV) System). He began using the device with standard oxygen therapy six months after being put on the transplant list.

“It was like night and day,” Jeff recalled. “Following treatment with NIOV, I could carry items up the stairs, instead of barely being able to climb them. And now I could spend five or more minutes on the elliptical machine, when before just being on it for a few seconds was impossible. Also, I was sleeping well again for the first time in months.”

The Breathe NIOV ventilator helped Jeff so much that he always made sure it was charged and on his person at all times. Eventually, when he and his wife were married in February, 2014, he was even able to go on a honeymoon while waiting for surgery, because his lung function had been stabilized and his endurance for physical activity improved.

Jeff had successful lung transplantation surgery in December, 2014, noting that “if I didn’t use the NIOV, at the rate I was going I wouldn’t have made it another 6 months, let alone a year and a half and still strong enough to survive the surgery.” While Jeff no longer needs to use the NIOV post-transplant, he stated, “Because I had the device, I was able to stay strong, which was a tremendous part of me recovering so well, and also keeping me alive that much longer.”

Two months after his lung transplant surgery, Jeff and his wife had their first child. While Jeff will always have CF, he has been increasingly active and is able to meet the hectic demands of life as a new father.

And he even finds the time to support to other people awaiting transplant. Even before his surgery, Jeff has been a mentor to other young people awaiting lung transplantation.

“It’s something I feel strongly about. A way to give back,” he said. “I am fortunate enough to be in a position to help some of my friends, who are faced with the challenges of being pre- or post-transplant. Having gone through this, I’m glad to have an opportunity to answer questions and be there for support.”

Asked what advice he’d give for others who are candidates for lung transplantation, “I’ve been very lucky, and had access to the right care, the right technology and the right timing. It’s a very scary process, but it’s important to remain optimistic. This is treatable and life can go on.”

In the near future, Jeff hopes to be able to continue the conversations he has had with the Lung Transplant Foundation (LTF) about starting a local chapter of the national Foundation in order to provide support to people living on the west coast who are waiting for surgery. Based in Raleigh, NC, the LTF’s mission is to promote and advance research in order to improve long-term outcomes among lung transplant recipients and to educate and promote awareness about organ donation. For more information please visit


WWII veteran visits Washington DC monuments using the NIOV System

Breathe Technologies sponsored WWII veteran Bob Scott on an Honor Flight to Washington, DC. Bob has COPD and he’s been using the NIOV System for three months. With the NIOV System, Bob says his exercise recovery time has gone from 30 minutes to eight minutes or less. He felt strong touring the monuments. Studies show veterans are at a higher risk of developing COPD. A tour of duty in the South Pacific may have contributed to Bob Scott’s COPD but nothing stopped him last weekend, as he joined the Honor Flight of Inland Empire’s trip to Washington, D.C. Bob says it’s easier to get around now that the Breathe NIOV has reduced his walking (exercise) recovery time.

“The Breathe NIOV provides additional volume to patients who are still short of breath even though they have adequate oxygen,” said Kathi Ellstrom, PhD, RN, ACNS-BC, a pulmonary clinical nurse specialist at Loma Linda VA Healthcare System. “When people cannot get enough air in their lungs, the non-invasive portable ventilator gives them the additional breath they need. Bob will use the NIOV during our visit to the monuments to help him feel less short of breath.”

Ellstrom will attend the September Honor Flight of Inland Empire trip as a guardian for Scott and two other veterans. Scott, who served as a midshipman in the Navy during World War II, began using the Breathe NIOV System three months ago.

“With COPD my lungs really deteriorated, everything just took so much longer. I was exhausted by daily chores and found I had to take around thirty minutes to rest between tasks just to recover,” said Scott. “But now that I use the Breathe NIOV System, my recovery time has been reduced to eight minutes or less. I’m sold on the technology and feel like I’ve gained my independence back.”

Scott is flying with the Honor Flight of Inland Empire and Breathe Technologies is the first corporate donor for this region. Local fundraising events and individual donors have historically provided the funding needed for the Honor Flight of Inland Empire’s trips.

“I’ve seen how difficult it is for people with COPD to make this trip and it’s wonderful to know that there’s something that will make it easier for them to enjoy their time visiting the monuments that were built to honor their service,” said Marva X, the fundraising chair for the Honor Flight of Inland Empire. “It’s doubly rewarding for us that the company that makes the device is also sponsoring veterans with COPD to go on the trip.”

“My father was a WWII veteran and it means a lot to all of us at Breathe to be able to support the greatest generation in this capacity,” said Larry Mastrovich, president and CEO, Breathe Technologies. “After everything they have done for our country, we are honored to enable Mr. Scott and other veterans to participate in the Honor Flight program.”


Answer on use of NIOV System with DC (12 V) power

We have had many questions regarding powering and charging the NIOV System with a DC (12 V) power outlet. We are excited to announce that the NIOV System can now be powered and charged while connected to any 12V outlet such as those available in a car. In order to connect the NIOV System’s AC charger to a 12V outlet, you will need to use a 75W (or higher) DC to AC power inverter. Breathe Technologies does not manufacture or sell DC power inverters for use with the NIOV System; however, they are readily available from your local retail electronic stores or online. An example for a 75 W DC power inverter would be the “Bestek 75 W Power Inverter” available on and other online retailers.

NIOV System – Transforming Patient Lives

Working for a medical device company that provides unique therapies that can have major positive impact on patients’ lives has many benefits. The main one is hearing from our patients about how our device changes their quality of lives. We have decided to occasionally share some of these moving and heart-warming voices in this section with you with hopes of increasing awareness and demonstrating how the NIOV System is helping patients living with respiratory insufficiency.

Patient Voices (Video): NIOV makes breathing easier for Robert

American Journal of Respiratory Critical Care Medicine (AJRCCM) publishes article on the NIOV System

The month of August has been a great month for the exposure of the NIOV System in clinical and patient communities.

The American Journal of Respiratory Critical Care Medicine (AJRCCM) published a peer-reviewed article by Porszasz et al., regarding the clinical effectiveness of the NIOV System to reduce dyspnea (shortness of breath), while significantly prolonging exercise endurance time and improving oxygen saturation (SpO2) levels in 15 COPD patients. This clinical research paper showed that COPD patients using the NIOV System were able to exercise 245% longer as compared to breathing on regular air (17.6 mins on NIOV vs. 5.5 min on air). When compared to traditional oxygen therapy, the NIOV System improved exercise endurance by 54% (11.4 mins on O2 therapy vs. 17.6 mins on NIOV). The patients’ heart rate and respiratory rate were also markedly reduced while using the NIOV system. Patients also reported significant improvement in their dyspnea score while at rest using the NIOV System.

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NIOV Oxygen Regulator with the hose and cylinder

Answers on NIOV Gas Source, Regulator, and Oxygen Consumption

When clinicians and patients first start learning about NIOV their questions often center around the gas source and its consumption. The NIOV System requires a 50-psi (with a minimum flow of 28 LPM) oxygen gas source to operate.

If you plan on using an oxygen cylinder as a gas source with the NIOV, a 50-psi regulator can be provided with the NIOV System or purchased from a third party vendor. The oxygen regulator provided with the NIOV System works with most oxygen cylinders (excluding the H-cylinder). If you decide to purchase your regulator from a third-party vendor, make sure that the regulator meets the NIOV System’s specifications.

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Breathe Technologies Sleep System Receives FDA Clearance

IRVINE, CALIFORNIA (May 30th 2013) Breathe Technologies, Inc., a manufacturer of innovative medical devices for people with respiratory conditions today announced the Food and Drug Administration (FDA) has granted the company 510(k) clearance to market its Sleep System (Continuous Positive Airway Pressure, or CPAP & Interface) in the US for treatment of Obstructive Sleep Apnea (OSA). The Breathe Sleep System utilizes miniaturized technologies coupled with user-centric design to provide a new therapeutic solution for patients with OSA.

“Reaching this milestone ahead of schedule is a testament to the expertise of our world-class  team,” said Larry Mastrovich, CEO of Breathe Technologies. “Our approach to respiratory care is centered on improving patients’ quality of life. Based on extensive research with patients and clinicians, we have designed a clinically effective system with unique features.”

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